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A comparison of the effects of diverse mutagens at the lacZ transgene and Dlb-1 locus in vivo.

Mutagenesis - 1 Jan 1999

Cosentino L, Heddle J A

Abstract excerpt

Transgenic assays permit the detection of mutations in any tissue, whereas endogenous mutations can be measured in very few. For this reason comparisons between these loci when both can be measured in the same cells are of considerable interest. Previous comparisons have been inconsistent: usually these loci have responded alike, however, in some cases the endogenous locus has been more sensitive and at other...

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PMID: 10474832
DOI: 10.1093/mutage/14.1.113

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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