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Article

Characterization of the first definitive hematopoietic stem cells in the AGM and liver of the mouse embryo.

Immunity - 1 Dec 1996

Sánchez M J, Holmes A, Miles C, Dzierzak E

Abstract excerpt

At day 10 in mouse gestation, the intraembryonic aorta-gonads-mesonephros (AGM) region generates the first definitive hematopoietic stem cells (HSCs) of the adult blood system. By 11 days postcoitum, the liver contains such HSCs. While HSCs of the adult bone marrow and late-stage fetal liver have...

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Identifiers

PMID: 8986712
DOI: 10.1016/s1074-7613(00)80267-8

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-8986712-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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