Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Mds1CreERT2, an inducible Cre allele specific to adult-repopulating hematopoietic stem cells.

Cell reports - 17 Aug 2021

Zhang Yi, McGrath Kathleen E, Ayoub Edward, Kingsley Paul D, Yu Hongbo, Fegan Kate, McGlynn Kelly A, Rudzinskas Sarah, Palis James, Perkins Archibald S

Abstract excerpt

Hematopoietic ontogeny consists of two broad programs: an initial hematopoietic stem cell (HSC)-independent program followed by HSC-dependent hematopoiesis that sequentially seed the fetal liver and generate blood cells. However, the transition from HSC-independent to HSC-derived hematopoiesis remains poorly characterized. To help resolve this question, we developed Mds1CreERT2 mice, which inducibly express...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Aging
Share to Cell Lineage

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Embryo, Mammalian

Share to Hematopoiesis

Share to Hematopoietic Stem Cells

Share to Integrases

Share to Tamoxifen

Source

Open in PubMed Open full text

Identifiers

PMID: 34407416
DOI: 10.1016/j.celrep.2021.109562
PMCID: PMC8428393

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Mds1CreERT2, an inducible Cre allele specific to adult-repopulating hematopoietic stem cells.PMID 34407416Read ↗

Embryonic hematopoiesis.Semantic proximity Read ↗

The Aorta-Gonad-Mesonephros niche shapes the functions of yolk sac-derived macrophages involved in hematopoietic stem and progenitor cell generation <i>ex vivo</i>Semantic proximity Read ↗

The evolving hematopoietic niche during developmentSemantic proximity Read ↗

Modeling human yolk sac hematopoiesis with pluripotent stem cellsSemantic proximity Read ↗

Yolk-Sac-Derived Macrophages Progressively Expand in the Mouse Kidney with AgeSemantic proximity Read ↗

The homeodomain protein Meis1 is essential for definitive hematopoiesis and vascular patterning in the mouse embryo.Semantic proximity Read ↗

Hematopoietic stem cells.Semantic proximity Read ↗

Isthmin 1 (ism1) is required for normal hematopoiesis in developing zebrafishSemantic proximity Read ↗

Human Induced Pluripotent Stem Cell-Derived Macrophages Share Ontogeny with MYB-Independent Tissue-Resident Macrophages.Semantic proximity Read ↗

Stem Cells, Hematopoiesis and Lineage Tracing: Transplantation-Centric Views and BeyondSemantic proximity Read ↗

How HSCs Colonize and Expand in the Fetal Niche of the Vertebrate Embryo: An Evolutionary PerspectiveSemantic proximity Read ↗

Highly potent human hematopoietic stem cells first emerge in the intraembryonic aorta-gonad-mesonephros regionSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.