Article
Phenotypic analysis and isolation of murine hematopoietic stem cells and lineage-committed progenitors.
Journal of visualized experiments : JoVE - 8 Jul 2012
Frascoli Michela, Proietti Michele, Grassi Fabio
Abstract excerpt
The bone marrow is the principal site where HSCs and more mature blood cells lineage progenitors reside and differentiate in an adult organism. HSCs constitute a minute cell population of pluripotent cells capable of generating all blood cell lineages for a life-time(1). The molecular dissection of HSCs homeostasis in the bone marrow has important implications in hematopoiesis, oncology and regenerative medicine....
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.