Article
Surface antigen phenotypes of hematopoietic stem cells from embryos and murine embryonic stem cells.
Blood - 9 Jul 2009
McKinney-Freeman Shannon L, Naveiras Olaia, Yates Frank, Loewer Sabine, Philitas Marsha, Curran Matthew, Park Peter J, Daley George Q
Abstract excerpt
Surface antigens on hematopoietic stem cells (HSCs) enable prospective isolation and characterization. Here, we compare the cell-surface phenotype of hematopoietic repopulating cells from murine yolk sac, aorta-gonad-mesonephros, placenta, fetal liver, and bone marrow with that of HSCs derived from the in vitro differentiation of murine embryonic stem cells (ESC-HSCs). Whereas c-Kit marks all HSC populations,...
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