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Emergence of intraembryonic hematopoietic precursors in the pre-liver human embryo

15 Feb 1999

Abstract excerpt

Hepatic hematopoiesis in the mouse embryo is preceded by two hematopoietic waves, one in the yolk sac, and the other in the paraaortic splanchnopleura, the presumptive aorta-gonad-mesonephros region that gives rise to prenatal and postnatal blood stem cells. An homologous intraembryonic site of stem cell emergence was previously identified at 5 weeks of human gestation, when hundreds of CD34(++ )Lin-...

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PMID: 9895326
DOI: 10.1242/dev.126.4.793

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