Article
Premature separation of centromere and aneuploidy: an indicator of high risk in unaffected individuals from familial breast cancer families?
European journal of cancer prevention : the official journal of the European Cancer Prevention Organisation (ECP) - 1 Oct 1996
Rao N M, Joshi N N, Shinde S R, Advani S H, Ghosh S N
Abstract excerpt
It is estimated that one in every four women with a first-degree relative affected by breast cancer will develop the disease. Recent evidence suggests that susceptibility to breast cancer can be inherited. We have carried out cytogenetic analysis on PHA-stimulated lymphocyte cultures of breast ca...
Topics
- Adult
- Aged
- Anaphase
- Aneuploidy
- Breast Neoplasms
- Case-Control Studies
- Cell Division
- Centromere
- Chromosome Aberrations
- Female
- Fibrocystic Breast Disease
- Genetic Predisposition to Disease
- Humans
- Lymphocyte Activation
- Male
- Middle Aged
- Pedigree
- Phytohemagglutinins