Article
Natural killer cell function and genetic instability in unaffected individuals from breast cancer families.
European journal of cancer prevention : the official journal of the European Cancer Prevention Organisation (ECP) - 1 Apr 1998
Shevde L A, Rao N M, Joshi N N, Shinde S R, Ghosh S N, Nadkarni J J
Abstract excerpt
Several recent reports highlight the importance of modifying factors in determining the risk for cancer of a person carrying a mutant allele of a tumour susceptibility gene. The study of two such risk modifying factors namely, natural killer (NK) cell function and constitutional cytogenetic anoma...
Topics
- Adult
- Breast Neoplasms
- Chromosome Aberrations
- Family Health
- Female
- Gene Expression Regulation, Neoplastic
- Genetic Predisposition to Disease
- Humans
- Killer Cells, Natural
- Male
- Middle Aged
- Mutation
- Pedigree
- Risk Factors