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Article

Variegated aneuploidy related to premature centromere division (PCD) is expressed in vivo and is a cancer-prone disease.

American journal of medical genetics - 22 Jan 2001

Plaja A, Vendrell T, Smeets D, Sarret E, Gili T, Català V, Mediano C, Scheres J M

Abstract excerpt

We present three patients with variegated aneuploidy and premature centromere division (PCD), a rare chromosomal abnormality in humans. Comparison of these three and eight other patients with variegated aneuploidy related to PCD demonstrates a phenotype comprising most frequently microcephaly, CNS anomalies (with cerebellar affection and migration defects), mental retardation, pre-and postnatal growth...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Identifiers

PMID: 11169558
DOI: 10.1002/1096-8628(20010122)98:3<216::aid-ajmg1091>3.0.co;2-0

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Source receipt: pubmed, retrieved 7 Sept 2026.

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