Article
Premature centromere division of the X chromosome in neurons in Alzheimer's disease.
Journal of neurochemistry - 1 Sept 2008
Spremo-Potparević Biljana, Zivković Lada, Djelić Ninoslav, Plećas-Solarović Bosiljka, Smith Mark A, Bajić Vladan
Abstract excerpt
Premature centromere division (PCD) represents a loss of control over the sequential separation and segregation of chromosome centromeres. Although first described in aging women, PCD on the X chromosome (PCD,X) is markedly elevated in peripheral blood lymphocytes of individuals suffering from Al...
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