Article
Inheritance of proliferative breast disease in breast cancer kindreds.
Science (New York, N.Y.) - 21 Dec 1990
Skolnick M H, Cannon-Albright L A, Goldgar D E, Ward J H, Marshall C J, Schumann G B, Hogle H, McWhorter W P, Wright E C, Tran T D
Abstract excerpt
Previous studies have emphasized that genetic susceptibility to breast cancer is rare and is expressed primarily as premenopausal breast cancer, bilateral breast cancer, or both. Proliferative breast disease (PBD) is a significant risk factor for the development of breast cancer and appears to be a precursor lesion. PBD and breast cancer were studied in 103 women from 20 kindreds that were selected for the...
Topics
- Adult
- Aged
- Breast Diseases
- Breast Neoplasms
- Female
- Genetic Predisposition to Disease
- Humans
- Male
- Menopause
- Middle Aged
- Pedigree