Article
[Centromere separation and malignancy].
Orvosi hetilap - 12 Nov 2000
Méhes K
Abstract excerpt
The centromeres of human chromosomes separate according to a "normal sequence" during mitosis. "Out-of-phase" separation and especially premature centromere division may lead to aneuploidy, and may be regarded as a manifestation of chromosome instability. Evaluation of these phenomena may contribute to a better understanding of predisposition to malignancy and to the possible screening of family members at high...
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