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Article

Sister chromatid exchange: A possible approach to characterize familial breast cancer patients.

Oncology reports - 1 Feb 2015

De Pascalis Ivana, Pilato Brunella, Mazzotta Annalisa, Dell'Endice Teresa Stefania, Rubini Vincenza, Simone Giovanni, Paradiso Angelo, Aiello Vincenzo, Mangia Anita

Abstract excerpt

Sister chromatid exchange (SCE) frequency is widely used as an indicator of spontaneous chromosome instability. We investigated SCE frequency in the peripheral blood lymphocytes of familial and sporadic breast cancer (BC) patients from the Apulian Caucasian Population. Eighty-one patients were enrolled: 22 with familial history and 59 sporadic patients. Eleven familial patients had an 'increased risk' of BRCA...

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Source

Identifiers

PMID: 25434423
DOI: 10.3892/or.2014.3628

Genes

BRCA2
BRCA1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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