Article
Analysis of the cellular origin of hepatocellular carcinoma by p53 genotype.
Journal of cancer research and clinical oncology - 1 Jan 1996
He B, Tang Z Y, Liu K D, Zhou G
Abstract excerpt
The polymerase chain reaction and HaeIII enzymatic digestion were used to study the seventh exon of the p53 gene in 29 primary and recurrent hepatomas in paraffin-embedded samples from 11 patients. The mutation rate of the p53 gene and its genotypes in samples of primary and recurrent tumours and...
Topics
- Adult
- Carcinoma, Hepatocellular
- Exons
- Genes, p53
- Genotype
- Humans
- Liver Neoplasms
- Middle Aged
- Mutation
- Neoplasm Recurrence, Local
- Paraffin Embedding
- Polymerase Chain Reaction
