Article
Analysis of the cellular origin of hepatocellular carcinoma by p53 genotype.
Journal of cancer research and clinical oncology - 1 Jan 1996
He B, Tang Z Y, Liu K D, Zhou G
Abstract excerpt
The polymerase chain reaction and HaeIII enzymatic digestion were used to study the seventh exon of the p53 gene in 29 primary and recurrent hepatomas in paraffin-embedded samples from 11 patients. The mutation rate of the p53 gene and its genotypes in samples of primary and recurrent tumours and multiple nodules were investigated. The cellular origins of hepatocellular carcinoma were analysed by p53 genotype....
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