Article
Is p53 gene mutation an indicatior of the biological behaviors of recurrence of hepatocellular carcinoma?
World journal of gastroenterology - 1 Jun 2003
Sheen I-Shyan, Jeng Kuo-Shyang, Wu Ju-Yann
Abstract excerpt
AIM: To evaluate mutant p53 gene in primary hepatocellular carcinoma and to investigate the correlation between it and the recurrence of hepatocellular carcinoma. METHODS: Mutations of p53 gene were examined using anti-human p53 monoclonal antibody and immunohistochemical staining in 79 resected hepatocellular carcinomas. The correlations among variables of p53 positivity and invasiveness, disease free interval...
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