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Article

Molecular characterization of p53 mutations in primary and secondary liver tumors: diagnostic and therapeutic perspectives.

Molecular biotechnology - 1 Jul 2002

Tullo Apollonia, Sbisà Elisabetta

Abstract excerpt

p53 is one of the most mutated genes in human cancer. We have performed the molecular characterization of p53 and have searched for correlations with etiological factors and clinical parameters in primary and secondary liver tumors. A systematic study was carried out, innovative in many respects, to determine the mutational pattern of all 11 exons of p53 and analysis was extended also to exons 1-4 and 9-11 and...

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Share to Carcinoma, Hepatocellular
Share to Exons
Share to Liver Neoplasms

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Mutation

Share to Polymorphism, Single-Stranded Conformational

Share to Sequence Analysis, DNA

Share to Survival Analysis

Share to Tumor Suppressor Protein p53

Source

Identifiers

PMID: 12102551
DOI: 10.1385/MB:21:3:265

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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