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Article

The significance of p53 mutations as an indicator of the biological behavior of recurrent hepatocellular carcinomas.

Surgery today - 1 Jan 1999

Sugo H, Takamori S, Kojima K, Beppu T, Futagawa S

Abstract excerpt

The significance of p53 mutations in the primary lesion for recurrent hepatocellular carcinoma (HCC) was evaluated. Mutations of p53 were examined using nonradioisotopic (nonRI)-polymerase chain reaction (PCR)-single strand conformation polymorphism (SSCP) in 98 resected HCCs. Of the 98 cases, 25 (26%) had a p53 mutation. In 83 patients who survived surgery, the presence of a p53 mutation was associated with a...

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Share to Carcinoma, Hepatocellular
Share to Liver Neoplasms
Share to Neoplasm Recurrence, Local

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Polymorphism, Single-Stranded Conformational

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Share to Tumor Suppressor Protein p53

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Identifiers

PMID: 10489124
DOI: 10.1007/BF02482774

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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