Mutation pattern of the p53 gene as a diagnostic marker for multiple hepatocellular carcinoma.

Article

Mutation pattern of the p53 gene as a diagnostic marker for multiple hepatocellular carcinoma.

Cancer research - 1 Jul 1992

Oda T, Tsuda H, Scarpa A, Sakamoto M, Hirohashi S

Abstract excerpt

Hepatocellular carcinoma, sometimes shows multiple tumor nodules, therefore poses a problem of differential diagnosis between cancers of multifocal and those of metastatic origin. Conventionally, pathological criteria have been used for this purpose, but these are largely subjective. In order to...

Topics

Base Sequence
Biomarkers, Tumor
Carcinoma, Hepatocellular
Diagnosis, Differential
Genes, p53
Humans
Liver Neoplasms
Molecular Sequence Data
Mutation
Neoplasms, Multiple Primary
Polymerase Chain Reaction

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