Article
Mutation pattern of the p53 gene as a diagnostic marker for multiple hepatocellular carcinoma.
Cancer research - 1 Jul 1992
Oda T, Tsuda H, Scarpa A, Sakamoto M, Hirohashi S
Abstract excerpt
Hepatocellular carcinoma, sometimes shows multiple tumor nodules, therefore poses a problem of differential diagnosis between cancers of multifocal and those of metastatic origin. Conventionally, pathological criteria have been used for this purpose, but these are largely subjective. In order to facilitate more objective differential diagnosis of multiple hepatocellular carcinoma, we used the pattern of mutation...
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