Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Analysis of the role of calmodulin binding and sequestration in neuromodulin (GAP-43) function.

The Journal of biological chemistry - 25 Oct 1996

Gamby C, Waage M C, Allen R G, Baizer L

Abstract excerpt

We demonstrated previously that forced expression of the neuronal phosphoprotein neuromodulin (also known as GAP-43, F1, B-50, and p57) in mouse anterior pituitary AtT-20 cells enhances depolarization-mediated secretion and alters cellular morphology. Here we analyze the role of calmodulin binding by neuromodulin in these responses. In cells expressing wild-type neuromodulin, a complex with calmodulin that is...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Calcium
Share to Cell Line
Share to Membrane Glycoproteins

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Mutation

Share to Nerve Tissue Proteins

Share to Neurons

Share to Phosphorylation

Source

Identifiers

PMID: 8900147
DOI: 10.1074/jbc.271.43.26698

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Analysis of the role of calmodulin binding and sequestration in neuromodulin (GAP-43) function.PMID 8900147Read ↗

Use of a two-hybrid system to investigate molecular interactions of GAP-43.Semantic proximity Read ↗

Mass spectrometric analysis of GAP-43/neuromodulin reveals the presence of a variety of fatty acylated species.Semantic proximity Read ↗

Calmodulin Binding to Connexin 35: Specializations to Function as an Electrical Synapse.Semantic proximity Read ↗

Calcineurin-mediated regulation of growth-associated protein 43 is essential for neurite and synapse formation and protects against α-synuclein-induced degenerationSemantic proximity Read ↗

Ca2+ binding protein-1 inhibits Ca2+ currents and exocytosis in bovine chromaffin cells.Semantic proximity Read ↗

Calcium-binding protein 1 is an inhibitor of agonist-evoked, inositol 1,4,5-trisphosphate-mediated calcium signaling.Semantic proximity Read ↗

Mutation of serine 41 in the neuron-specific protein B-50 (GAP-43) prohibits phosphorylation by protein kinase C.Semantic proximity Read ↗

Phosphomimetic mutation of Ser-187 of SNAP-25 increases both syntaxin binding and highly Ca2+-sensitive exocytosis.Semantic proximity Read ↗

DOC2B acts as a calcium switch and enhances vesicle fusion.Semantic proximity Read ↗

Disruption of Rab3-calmodulin interaction, but not other effector interactions, prevents Rab3 inhibition of exocytosis.Semantic proximity Read ↗

A point mutant of GAP-43 induces enhanced short-term and long-term hippocampal plasticity.Semantic proximity Read ↗

Ca(2+)-induced recruitment of the secretory vesicle protein DOC2B to the target membrane.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.