Calcium-binding protein 1 is an inhibitor of agonist-evoked, inositol 1,4,5-trisphosphate-mediated calcium signaling.

doi:10.1074/jbc.M309617200

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Article

Calcium-binding protein 1 is an inhibitor of agonist-evoked, inositol 1,4,5-trisphosphate-mediated calcium signaling.

The Journal of biological chemistry - 2 Jan 2004

Haynes Lee P, Tepikin Alexei V, Burgoyne Robert D

Abstract excerpt

Intracellular calcium signals are responsible for initiating a spectrum of physiological responses. The caldendrins/calcium-binding proteins (CaBPs) represent mammal-specific members of the CaM superfamily. CaBPs display a restricted pattern of expression in neuronal/retinal tissues, suggesting a specialized role in Ca2+ signaling in these cell types. Recently, it was reported that a splice variant of CaBP1...

Topics

Alternative Splicing
Animals
Calcium Signaling
Calcium-Binding Proteins
Cloning, Molecular
Genetic Variation
Humans
Inositol 1,4,5-Trisphosphate
Kinetics
Neuronal Calcium-Sensor Proteins
Neuropeptides

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

PC12 Cells

Polymerase Chain Reaction

Rats

Recombinant Proteins

Signal Transduction

Transfection

Source

Open in PubMed

Identifiers

PMID: 14570872
DOI: 10.1074/jbc.M309617200

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-14570872-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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