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Article

Mass spectrometric analysis of GAP-43/neuromodulin reveals the presence of a variety of fatty acylated species.

The Journal of biological chemistry - 6 Sept 2002

Liang Xiquan, Lu Yun, Neubert Thomas A, Resh Marilyn D

Abstract excerpt

GAP-43 (neuromodulin) is a protein kinase C substrate that is abundant in developing and regenerating neurons. Thioester-linked palmitoylation at two cysteines near the GAP-43 N terminus has been implicated in directing membrane binding. Here, we use mass spectrometry to examine the stoichiometry of palmitoylation and the molecular identity of the fatty acid(s) attached to GAP-43 in vivo. GAP-43 expressed in...

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PMID: 12105219
DOI: 10.1074/jbc.M204607200

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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