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Article

Effects of P2 cleavage site mutations on poliovirus polyprotein processing.

Virology - 1 Oct 1996

Cohen L, Kean K M, Girard M, Van der Werf S

Abstract excerpt

The poliovirus genome comprises a single open reading frame which is translated to give one large polyprotein. The proteolytic cascade involved in the processing of this polyprotein is not yet understood in full detail,particularly concerning the processing of P2-P3, the precursor to the viral nonstructural polypeptides, 2A, 2B, 2C, 3A, 3B, 3C, and 3D. To investigate the possibility that the cleavage events...

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Identifiers

PMID: 8862397
DOI: 10.1006/viro.1996.0504

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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