Article
The capsid of infectious bursal disease virus contains several small peptides arising from the maturation process of pVP2.
Journal of virology - 1 Mar 2002
Da Costa Bruno, Chevalier Christophe, Henry Celine, Huet Jean-Claude, Petit Stéphanie, Lepault Jean, Boot Hein, Delmas Bernard
Abstract excerpt
The capsid proteins VP2 and VP3 of infectious bursal disease virus, a birnavirus, are derived from the processing of a large polyprotein: NH2-pVP2-VP4-VP3-COOH. Although the primary cleavage sites at the pVP2-VP4 and VP4-VP3 junctions have been identified, the proteolytic cascade involved in the processing of this polyprotein is not yet fully understood, particularly the maturation of pVP2. By using different...
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