Article
Escherichia coli translation initiation factor 3 discriminates the initiation codon in vivo.
Molecular microbiology - 1 Jul 1996
Sussman J K, Simons E L, Simons R W
Abstract excerpt
In a genetic selection designed to isolate Escherichia coli mutations that increase expression of the IS 10 transposase gene (tnp), we unexpectedly obtained viable mutants defective in translation initiation factor 3 (IF3). Several lines of evidence led us to conclude that transposase expression, per se, was not increased. Rather, these mutations appear to increase expression of the tnp'-'lacZ gene fusions used...
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