Article
Case for the genetic code as a triplet of triplets.
Proceedings of the National Academy of Sciences of the United States of America - 2 May 2017
Chevance Fabienne F V, Hughes Kelly T
Abstract excerpt
The efficiency of codon translation in vivo is controlled by many factors, including codon context. At a site early in the Salmonella flgM gene, the effects on translation of replacing codons Thr6 and Pro8 of flgM with synonymous alternates produced a 600-fold range in FlgM activity. Synonymous changes at Thr6 and Leu9 resulted in a twofold range in FlgM activity. The level of FlgM activity produced by any codon...
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