Article
IF3-mediated suppression of a GUA initiation codon mutation in the recJ gene of Escherichia coli.
Journal of bacteriology - 1 Nov 1997
Haggerty T J, Lovett S T
Abstract excerpt
A mutational change of the initiation codon to GUA was found to reduce, but not abolish, expression of the recJ gene of Escherichia coli. Specific mutations in translational initiation factor IF3 have been isolated as second-site suppressors of this GUA initiation codon mutation. One of these, infC135, with an arginine-to-proline change at amino acid 131, completely restores a wild-type phenotype to recJ GUA...
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