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Article

Mutations that alter initiation codon discrimination by Escherichia coli initiation factor IF3.

Journal of molecular biology - 21 May 1999

Sacerdot C, de Cock E, Engst K, Graffe M, Dardel F, Springer M

Abstract excerpt

This work describes the isolation of mutations in infC, the structural gene for IF3, using different genetic screens. Among 21 mutants characterised, seven were shown to produce stable variant IF3 proteins unable to fully complement a strain carrying a chromosomal deletion of the infC gene. The mutants were also shown to be unable to normally discriminate against several non-canonical initiation codons such as...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Identifiers

PMID: 10329180
DOI: 10.1006/jmbi.1999.2737

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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