Article
Global analysis of translation termination in E. coli.
PLoS genetics - 1 Mar 2017
Baggett Natalie E, Zhang Yan, Gross Carol A
Abstract excerpt
Terminating protein translation accurately and efficiently is critical for both protein fidelity and ribosome recycling for continued translation. The three bacterial release factors (RFs) play key roles: RF1 and 2 recognize stop codons and terminate translation; and RF3 promotes disassociation of bound release factors. Probing release factors mutations with reporter constructs containing programmed frameshifting...
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