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Article

Mapping the active sites of bacterial translation initiation factor IF3.

Journal of molecular biology - 15 Aug 2003

Petrelli Dezemona, Garofalo Cristiana, Lammi Matilde, Spurio Roberto, Pon Cynthia L, Gualerzi Claudio O, La Teana Anna

Abstract excerpt

IF3C is the C-terminal domain of Escherichia coli translation initiation factor 3 (IF3) and is responsible for all functions of this translation initiation factor but for its ribosomal recycling. To map the number and nature of the active sites of IF3 and to identify the essential Arg residue(s) chemically modified with 2,3-butanedione, the eight arginine residues of IF3C were substituted by Lys, His, Ser and...

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Identifiers

PMID: 12899827
DOI: 10.1016/s0022-2836(03)00731-9

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Mapping the active sites of bacterial translation initiation factor IF3.PMID 12899827Read ↗

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