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Article

IF2 and unique features of initiator tRNAfMet help establish the translational reading frame.

RNA biology - 1 Jan 2018

Roy Bappaditya, Liu Qi, Shoji Shinichiro, Fredrick Kurt

Abstract excerpt

Translation begins at AUG, GUG, or UUG codons in bacteria. Start codon recognition occurs in the P site, which may help explain this first-position degeneracy. However, the molecular basis of start codon specificity remains unclear. In this study, we measured the codon dependence of 30S•mRNA•tRNAfMet and 30S•mRNA•tRNAMet complex formation. We found that complex stability varies over a large range with initiator...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 28914580
DOI: 10.1080/15476286.2017.1379636
PMCID: PMC6103701

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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