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Article

Induction of mutagenic DNA damage by chromium (VI) and glutathione.

Environmental and molecular mutagenesis - 1 Jan 1996

Liu S, Dixon K

Abstract excerpt

Certain chromium (Cr) compounds are known to be carcinogenic in humans and mutagenic in cell culture. However, the mechanism of Cr mutagenesis is not well understood. It appears that intracellular reduction of Cr by agents such as glutathione plays a role in the induction of DNA damage. We have used a simian virus 40-based shuttle vector to investigate the relationship between chromium-induced DNA damage and Cr...

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Identifiers

PMID: 8844987
DOI: 10.1002/(SICI)1098-2280(1996)28:2<71::AID-EM2>3.0.CO;2-H

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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