Article
Mutations induced by glyoxal and methylglyoxal in mammalian cells.
Nucleic acids symposium series - 1 Jan 2000
Murata-Kamiya N, Kamiya H, Kaji H, Kasai H
Abstract excerpt
To investigate the mutation spectra of glyoxal and methylglyoxal in mammalian cells, we analyzed mutations in a bacterial suppressor tRNA (supF) gene in the shuttle vector plasmid pMY189. The cytotoxicity and the mutation frequency increased according to the doses of glyoxal and methylglyoxal. Th...
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