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Article

Vitamin C prevents DNA mutation induced by oxidative stress.

The Journal of biological chemistry - 10 May 2002

Lutsenko Eugene A, Cárcamo Juan M, Golde David W

Abstract excerpt

The precise role of vitamin C in the prevention of DNA mutations is controversial. Although ascorbic acid has strong antioxidant properties, it also has pro-oxidant effects in the presence of free transition metals. Vitamin C was recently reported to induce the decomposition of lipid hydroperoxides independent of metal interactions, suggesting that it may cause DNA damage. To directly address the role of vitamin...

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PMID: 11884413
DOI: 10.1074/jbc.M201151200

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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