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Article

Killing of chromium-damaged cells by mismatch repair and its relevance to carcinogenesis.

Cell cycle (Georgetown, Tex.) - 1 Aug 2005

Zhitkovich Anatoly, Peterson-Roth Elizabeth, Reynolds Mindy

Abstract excerpt

Hexavalent chromium compounds are widespread environmental contaminants that are well recognized as human carcinogens and potent respiratory toxicants. Intracellular metabolism of chromium(VI) leads to the production of numerous chromium-DNA adducts that are primarily formed at the phosphate groups. The mechanism of toxicity of these DNA modifications in human cells has been uncertain for a long time because...

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PMID: 15970712

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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