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Article

Biological testing versus sequence analysis for determination of drug resistance of human immunodeficiency virus.

Zentralblatt fur Bakteriologie : international journal of medical microbiology - 1 Jul 1996

Wichers M, Kaiser R, Rockstroh J, Matz B, Schneweis K E

Abstract excerpt

Resistance of HIV-1 to 3'-azido-3'-deoxythymidine (AZT) is associated with one or more of five mutations in the reverse transcriptase (RT) segment of the polymerase gene ("AZT-specific mutations"). Therefore, sequence analysis of the proviral DNA, derived directly from the blood, is considered to replace the biological test. Additional arguments are non-cultivatable viral strains, the universality of the sequence...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 8837404
DOI: 10.1016/s0934-8840(96)80119-8

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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