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Article

In vitro selection of human immunodeficiency virus type 1 resistant to 3'-azido-3'-deoxythymidine.

Antiviral research - 1 May 1992

Dianzani F, Antonelli G, Turriziani O, Dong G, Capobianchi M R, Riva E

Abstract excerpt

3'-Azido-3'-deoxythymidine (AZT)-resistant human immunodeficiency virus type 1 (HIV-1) was obtained by growing HTLV-IIIB in C8166 cell cultures in the presence of inhibitory concentrations of AZT. The AZT-resistant HIV-1 was capable of replicating, as measured by infectious virus yield, and inducing cytopathic effect in the presence of AZT concentrations able to completely suppress the replication of parental...

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Identifiers

PMID: 1384427
DOI: 10.1016/0166-3542(92)90004-o

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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In vitro selection of human immunodeficiency virus type 1 resistant to 3'-azido-3'-deoxythymidine.PMID 1384427Read ↗

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