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Article

In vivo comparison of zidovudine resistance mutations in blood and CSF of HIV-1-infected patients.

Neurology - 1 Dec 1993

Wildemann B, Haas J, Ehrhart K, Wagner H, Lynen N, Storch-Hagenlocher B

Abstract excerpt

Several mutations are associated with resistance to zidovudine (3'-azido-3'-deoxythymidine, AZT) in cultured human immunodeficiency virus type 1 (HIV-1) isolates. Little is known as to what extent drug resistance occurs in vivo and whether its development within the CNS differs from that in peripheral blood. We therefore performed comparative nucleotide sequence analysis of the HIV-1 reverse transcriptase (RT)...

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Identifiers

PMID: 7504798
DOI: 10.1212/wnl.43.12.2659

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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