Susceptibility of HIV-1 isolates to zidovudine: correlation between widely applicable culture test and PCR analysis.

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Article

Susceptibility of HIV-1 isolates to zidovudine: correlation between widely applicable culture test and PCR analysis.

Journal of acquired immune deficiency syndromes - 1 Jan 1992

Jung M, Agut H, Candotti D, Ingrand D, Katlama C, Huraux J M

Abstract excerpt

Thirteen isolates of human immunodeficiency virus type 1 (HIV-1) obtained in coculture with peripheral blood lymphocytes were tested for in vitro susceptibility to zidovudine (ZDV). Seven isolates were obtained from patients who had never been treated with ZDV and six from patients receiving the...

Topics

Base Sequence
Drug Resistance, Microbial
HIV Reverse Transcriptase
HIV-1
Humans
Lymphocytes
Microbial Sensitivity Tests
Molecular Sequence Data
Mutation
Polymerase Chain Reaction
RNA-Directed DNA Polymerase
Zidovudine

Source

Open in PubMed

Identifiers

PMID: 1372352

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-1372352-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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