Article
Sequence diversity of the reverse transcriptase of human immunodeficiency virus type 1 from untreated Brazilian individuals.
Antimicrobial agents and chemotherapy - 1 Jul 1999
Brindeiro R, Vanderborght B, Caride E, Correa L, Oravec R M, Berro O, Stuyver L, Tanuri A
Abstract excerpt
The presence of human immunodeficiency virus type 1 (HIV-1) bearing mutations resistant to nucleosidic inhibitors of the viral reverse transcriptase (RT) derived from HIV-seropositive asymptomatic and untreated volunteer blood donors was examined. The RT amplicons of 32 specimens were analyzed by using a reverse hybridization line probe assay technique that detects resistance against zidovudine...
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