Article
Determination of CYP2C19 phenotype in black Americans with omeprazole: correlation with genotype.
Clinical pharmacology and therapeutics - 1 Aug 1996
Marinac J S, Balian J D, Foxworth J W, Willsie S K, Daus J C, Owen R, Flockhart D A
Abstract excerpt
BACKGROUND: Our objective was to study omeprazole as a single-dose oral probe in the determination of CYP2C19 phenotype in black subjects and to determine the correlation between phenotype and genotype. METHODS: This single-dose, open-label outpatient study was conducted at a community-based, university-affiliated teaching hospital outpatient clinic. Study subjects were 100 healthy, unrelated black adults (age...
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