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Article

CYP2C19 genotype and phenotype determined with omeprazole in patients with acid-related disorders with and without Helicobacter pylori infection.

Scandinavian journal of gastroenterology - 1 Oct 1998

Sagar M, Seensalu R, Tybring G, Dahl M L, Bertilsson L

Abstract excerpt

BACKGROUND: Omeprazole is to a major extent metabolized by cytochrome P450 isozyme CYP2C19. The aims of this study were to compare the phenotype of CYP2C19 determined by omeprazole with the genotype and to determine the effect of Helicobacter pylori infection on the metabolism of omeprazole. METH...

Topics

Anti-Ulcer Agents
Aryl Hydrocarbon Hydroxylases
Chromatography, High Pressure Liquid
Cytochrome P-450 CYP2C19
Cytochrome P-450 Enzyme System
Enzyme-Linked Immunosorbent Assay
Female
Gastroesophageal Reflux
Genotype
Helicobacter Infections

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Helicobacter pylori

Humans

Male

Middle Aged

Mixed Function Oxygenases

Mutation

Omeprazole

Peptic Ulcer

Source

Identifiers

PMID: 9829356
DOI: 10.1080/003655298750026714

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-9829356-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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