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Article

Genetic polymorphism of (S)-mephenytoin 4'-hydroxylation in populations of African descent.

British journal of clinical pharmacology - 1 Sept 1999

Xie H G, Kim R B, Stein C M, Wilkinson G R, Wood A J

Abstract excerpt

AIMS: The frequency of CYP2C19 poor metabolizers (PMs) in populations of African descent has been reported to range from 1.0% to 35.4%. In order to determine with greater certainty the frequency of CYP2C19 PMs in such black populations we have performed a meta-analysis of the studies. METHODS: Relevant data on the frequency of both the PM phenotype of probe drugs (mephenytoin, omeprazole, and proguanil), and the...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 10510153
DOI: 10.1046/j.1365-2125.1999.00009.x
PMCID: PMC2014331

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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