Article
Correspondence between the CYP2C19 and CYP3A4 genotypes with the inferred metabolizer phenotype by omeprazole administration in Mexican healthy children.
Journal of clinical pharmacy and therapeutics - 1 Oct 2018
Favela-Mendoza A F, Martínez-Cortes G, Romero-Prado M M, Romero-Tejeda E M, Islas-Carbajal M C, Sosa-Macias M, Lares-Asseff I, Rangel-Villalobos H
Abstract excerpt
WHAT IS KNOWN AND OBJECTIVE: CYP2C19 genotypes presumably allow the prediction of the metabolizer phenotypes: poor (PMs), extensive (EMs) and ultra-rapid (UMs). However, evidence from previous studies regarding this predictive power is unclear, which is important because the benefits expected by healthcare institutions and patients are based on this premise. Therefore, we aimed to complete a formal evaluation of...
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