Article
Association of allelic losses on human chromosomal arms 11Q and 16Q in sporadic breast cancer.
International journal of cancer - 22 Aug 1996
Schmutzler R K, Fimmers R, Bierhoff E, Lohmar B, Homann A, Speiser P, Kubista E, Jaeger K, Krebs D, Zeillinger R, Wiestler O D, Von Deimling A
Abstract excerpt
Breast-carcinoma development presumably results from multiple mutational events in tumor-associated genes. Certain results indicate that some tumor-suppressor genes may combine their pathogenetic potential to synergistically promote tumor growth. In an effort to identify such mechanisms in breast tumors, a series of 77 (group I) paired blood tumor samples from patients with sporadic mammary carcinomas was...
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