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Article

Loss of heterozygosity at selective sites on chromosomes 13 and 17 in human breast carcinoma.

Anticancer research - 1 Jan 2000

Thorlacius S, Jonasdottir O, Eyfjord J E

Abstract excerpt

Four chromosomal regions were tested for loss of constitutional heterozygosity in primary tumours from 85 Icelandic breast cancer patients. Loss of heterozygosity and other types of gene rearrangements were observed in 37% of informative cases at the retinoblastoma locus, RB1, on chromosome 13q. Allele losses on chromosome 17 were tested with two polymorphic probes on 17p and two on 17q. Loss of heterozygosity or...

Topics

Alleles
Blotting, Southern
Breast Neoplasms
Chromosome Aberrations
Chromosome Banding
Chromosome Deletion
Chromosome Disorders
Chromosomes, Human, Pair 13
Chromosomes, Human, Pair 17
DNA, Neoplasm
Female

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Gene Rearrangement

Heterozygote

Humans

Middle Aged

Source

Identifiers

PMID: 1746906

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-1746906-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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Loss of heterozygosity at selective sites on chromosomes 13 and 17 in human breast carcinoma.PMID 1746906Read ↗

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