Allelotype of human breast carcinoma: a second major site for loss of heterozygosity is on chromosome 6q.

Article

Allelotype of human breast carcinoma: a second major site for loss of heterozygosity is on chromosome 6q.

Oncogene - 1 Sept 1991

Devilee P, van Vliet M, van Sloun P, Kuipers Dijkshoorn N, Hermans J, Pearson P L, Cornelisse C J

Abstract excerpt

Loss of heterozygosity (LOH), which is detected with polymorphic DNA markers by comparing constitutional and tumor genotypes, has been observed at a number of different chromosome arms in primary breast tumors. These include 1p, 1q, 3p, 11p, 13q, 17p and 18q. We present here the results of a scre...

Topics

Alleles
Blotting, Southern
Breast Neoplasms
Chromosomes, Human, Pair 6
DNA, Neoplasm
Female
Genetic Markers
Genotype
Heterozygote
Humans
Polymorphism, Restriction Fragment Length

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