Article
Allelotype of human breast carcinoma: a second major site for loss of heterozygosity is on chromosome 6q.
Oncogene - 1 Sept 1991
Devilee P, van Vliet M, van Sloun P, Kuipers Dijkshoorn N, Hermans J, Pearson P L, Cornelisse C J
Abstract excerpt
Loss of heterozygosity (LOH), which is detected with polymorphic DNA markers by comparing constitutional and tumor genotypes, has been observed at a number of different chromosome arms in primary breast tumors. These include 1p, 1q, 3p, 11p, 13q, 17p and 18q. We present here the results of a screening of all non-acrocentric chromosome arms, including those of the X chromosome, with at least one polymorphic marker...
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