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Article

Patterns of allele losses suggest the existence of five distinct regions of LOH on chromosome 17 in breast cancer.

International journal of cancer - 15 Jan 1994

Kirchweger R, Zeillinger R, Schneeberger C, Speiser P, Louason G, Theillet C

Abstract excerpt

Chromosome 17 is a frequent target during breast-cancer formation and progression. It has been shown to be affected by allele losses at multiple sites, as well as by DNA amplification. Our aim was to delineate a map of the genetic alterations on chromosome 17 in a given set of breast tumors. To this end we analyzed 151 pairs of tumor and cognate lymphocyte DNAs by Southern blotting with 5 RFLP or VNTR probes and...

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Source

Identifiers

PMID: 8314300
DOI: 10.1002/ijc.2910560208

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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