Article
Allelic imbalance study of 16q in human primary breast carcinomas using microsatellite markers.
Genes, chromosomes & cancer - 1 Nov 1995
Dorion-Bonnet F, Mautalen S, Hostein I, Longy M
Abstract excerpt
The high incidence of allelic imbalance on the long arm of chromosome 16 in breast cancer suggests its involvement in the development and progression of the tumor. Several loss of heterozygosity (LOH) studies have led to the assignment of commonly deleted regions on 16q where tumor suppressor gen...
Topics
- Adult
- Aged
- Alleles
- Breast Neoplasms
- Carcinoma, Ductal, Breast
- Carcinoma, Lobular
- Cell Differentiation
- Chromosomes, Human, Pair 16
- DNA, Neoplasm
- Disease Progression
- Female
- Genes, Tumor Suppressor
- Genetic Markers
- Humans
- Microsatellite Repeats
- Middle Aged
- Polymerase Chain Reaction
- Sequence Deletion