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Article

P- and E-selectin-deficient mice are susceptible to cerebral ischemia-reperfusion injury.

Brain research - 24 Jul 1999

Soriano S G, Wang Y F, Wagner D D, Frenette P S

Abstract excerpt

We examined brain sections from P- and E-selectin-deficient mice (-/-) and their nontransgenic littermates (+/+) after focal cerebral ischemia and reperfusion (I/R) tissue injury. There was no difference in the subsequent infarct volume after 3 h of ischemia and 21 h of reperfusion. These data indicate that selectin-independent mechanisms mediate tissue injury after a prolonged period of transient focal ischemia.

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Source

Identifiers

PMID: 10415396
DOI: 10.1016/s0006-8993(99)01637-6

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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