Article
Optimal selectin-mediated rolling of leukocytes during inflammation in vivo requires intercellular adhesion molecule-1 expression.
Proceedings of the National Academy of Sciences of the United States of America - 23 Jun 1998
Steeber D A, Campbell M A, Basit A, Ley K, Tedder T F
Abstract excerpt
Leukocyte interactions with vascular endothelium during inflammation occur through discrete steps involving selectin-mediated leukocyte rolling and subsequent firm adhesion mediated by members of the integrin and Ig families of adhesion molecules. To identify functional synergy between selectin and Ig family members, mice deficient in both L-selectin and intercellular adhesion molecule 1 (ICAM-1) were generated....
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